Isogenic.info has two sub-sites plus a single page on animal models and the author.
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My new web site (3Rs-reduction.co.uk) is designed to help scientists teach themselves the principles of designing experiments involving laboratory animals. It is still under development, but you can try it now.
Michael Festing, 16th. Feb. 2012
Design
This sub-web describes 15 steps in the design and statistical analysis of experiments involving laboratory animals. Such experiments could frequently be designed better, leading to a saving in animals, cost, time and effort, and improving the scientific quality of the results.
Isogenic
Isogenic strains (inbred strains and F1 hybrids) have made a substantial contribution to biomedical research. This sub-web describes their properties and characteristics and contrasts them with the genetically heterogeneous “outbred” stocks of mice and rats which are still widely used in biomedical research. It makes the case that the use of outbred stocks should be discontinued unless specifically justified for a particular research application.
Animal models
This is a single page on the philosophy of animal models
Genetics and toxicity testing.
Toxicologists usually use a single stock of outbred mice or rats for screening potential new drugs or environmental chemicals. They ignore genetic variation in their test animals. This is poor science and may well account for the poor record of animal toxicity testing. Click here. to go directly to the page which explains this.
Experiments on animals are necessary in order to ensure the safety of products, cosmetics, and household chemicals. They are also used to develop new methods of testing new medical substances for different diseases’ treatment. In fact, experiments on animals are completely unsuitable for these purposes. They do not allow assessing whether the use of certain…
My Canadian Pharmacy is one of the most popular drug providers in the world. The store is operating online and offers to deliver high-quality medications to the customer’s address. Today, we publish a brief company review by medical experts. Products This online pharmacy sells generic medications. They have over 30 drug categories on their website….
In real life, pharmacies in which you can buy the necessary medications, differ in the income of the clients: high, average and low. In an expensive pharmacy chain, not everyone can afford to buy medications, because the prices are simply “high-scraper.” With regard to the budget pharmacy, there is no full guarantee that you can…
Erectile dysfunction (ED) is a medical condition that often goes untreated in millions of men across Canada and the world. It is a condition that many men feel too embarrassed to talk to their doctors about. As a result, only a handful of men get the treatment they truly need. Over the counter medication from…
Zoloft is a drug used as an antidepressant. The active ingredient of the drug is sertraline, which works on the chemicals in the brain to create equilibrium for a calm state of mind. Zoloft belongs to the selective serotonin reuptake inhibitors (SSRIs) class of drugs. Some of the diseases or mental state where Zoloft is used…
If you want to order medications from the comfort of your home or office, you can use the website of My Canadian Pharmacy. This online pharmacy offers a high range of medications. Here you can buy antibiotics, men’s health drugs, medicine for women’s health, birth control pills, herbal supplements, and many other products. This store has…
Studies have shown that men who regularly rely on painkillers have a higher risk of suffering from erectile dysfunction (ED) than their peers who don’t take painkillers regularly. Erectile dysfunction is a medical condition whereby the system that allows a man to maintain an erection is disrupted by one or several causes. The hormones, the…